一、基本信息
叶晓雪,副教授,博士生导师,beat365官方网站分子诊断与精准治疗研究中心副主任,入选湖北省青年人才项目,湖北省女科技工作者协会理事。近年来围绕脑部化学测量,开发了一系列基于微电极植入的活体脑化学信号实时监测新技术,开展了脑化学信号与脑功能、脑疾病的相关研究。主持国家自然科学基金项目2项,参与基金委重大仪器研制项目1项,获批纵向科研经费超过300万元。以第一/通讯作者身份在Angew. Chem. Int. Ed.、Chem. Sci.、Adv. Funct. Mater.等期刊发表论文十余篇。
电子邮件:yexxchem@hubu.edu.cn
二、教育背景及工作经历
2003.09—2007.06 华中师范大学化学学院,化学,本科
2007.09—2010.06 华中师范大学化学学院,分析化学,硕士,
2010.10—2013.11 日本广岛大学,应用化学,博士
2014.01—2018.12 中南民族大学化学与材料科学学院,讲师
2019.01—2022.09 beat365官方网站化学化工学院,讲师、副教授
2022.09—至今 beat365官方网站beat365亚洲体育在线,副教授
三、研究方向
主要研究方向包括:光/电化学微纳传感,面向脑部的光电化学活体分析,环境污染暴露下的生物毒性效应原位分析等。
四、科研项目(近五年)
1. 国家自然科学基金面上项目,2023.01-2026.12,54万元,主持;
2. 国家基金委国家重大科研仪器研制项目,2023.01-2027.12,beat365官方网站负责人(130.5万元,项目总经费770万元);
3. 湖北省“青年拔尖人才计划”,2022.11-2025.10,60万元,主持;
4. 国家自然科学基金青年项目,2020.01-2022.12,26万元,主持,已结题;
5. 波谱与原子分子物理国家重点实验室课题,2021.08-2024.07,5万元,主持;
6. 湖北省博士后创新研究岗位项目,2019.01-2019.12,6万,主持,已结题;
7. 山东省肿瘤标志物检测技术重点实验室开放课题,2019.01-2019.12,5万元,主持,已结题。
五、近5年代表性论文
1. Xiao Wang, Tao Lu, Zirui Cai, Dongfang Han, Xiaoxue Ye*, Zhihong Liu*, A Photoelectrochemical Sensor for Real-Time Monitoring of Neurochemical Signals in the Brain of Awake Animals, Anal. Chem. 2024, , DOI: 10.1021/acs.analchem.4c00934.
2. Danying Lin, Tao Lu, Xiao Wang, Xiaoxue Ye*, Zhihong Liu*, Reversible Photoelectrochemical Microsensor for Dynamically Monitoring Sulfur Dioxide in Epileptic Brain, Chem. Sci, 2024, 15, 4824-4832.
3. Han Wang, Caoling Li, Jingwei Zhang, Zhao Yang, Junjun Li, Yu Cao, Kangbing Wu, Zhihong Liu, Junxing Hao*, Xiaoxue Ye*, NIR-Excitable POM-Encapsulated Yb-Bi2S3 Decorated Graphene for Wearable Photoelectrochemical Sensing, Adv. Funct. Mater. 2024, DOI: 10.1002/adfm.202315917
4. Yao Kong, Zirui Cai, Shizhen Chen, Xiaoxue Ye*, Zhihong Liu, Small molecule probes as versatile energy acceptors: A breakthrough in photoelectrochemical sensing for sulfur dioxide recording in rat brain, Biosens. Bioelectron., 2024, 243, 115760.
5. Lixia Tao, Yao Kong, Yunhui Xiang, Yu Cao, Xiaoxue Ye*, Zhihong Liu*, Implantable optical fiber microelectrode with anti-biofouling ability for in vivo photoelectrochemical analysis, Chin. Chem. Lett. 2023, 34, 107481.
6. Xiaoxue Ye; Xing Wang; Yao Kong; Mengjiao Dai; Dongxue Han*; Zhihong Liu*; FRET modulated signaling: a versatile strategy to construct photoelectrochemical microsensors for in vivo analysis, Angew. Chem. Int. Ed. 2021, 60, 11774-11778.
7. Yunhui Xiang, Yao Kong, Wenqi Feng, Xiaoxue Ye*, Zhihong Liu*, Ratiometric photoelectrochemical microsensor based on small-molecule organic semiconductor for reliable in vivo analysis, Chem. Sci. 2021, 12, 12977-12984.
8. Xiaoxue Ye#, Yunhui Xiang#, Qirong Wang, Zhen Li*, Zhihong Liu*, A Red emissive two-photon fluorescence probe based on carbon dots for intracellular pH detection, Small, 2019, 15, 1901673.
9. Yanying Wang, Chunya Li, Tsunghsueh Wu, Xiaoxue Ye*, Polymerized ionic liquid functionalized graphene oxide nanosheets as a sensitive platform for bisphenol A sensing, Carbon 2018, 129, 21-28.